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E. coli RNA polymerase accurately transcribed an 8 letter synthetic DNA alphabet instead of the normal 4

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https://today.ucsd.edu/story/breakthrough-helps-expand-genetic-alphabet

Breakthrough Helps Expand Genetic Alphabet
today.ucsd.eduBreakthrough Helps Expand Genetic Alphabet Researchers at UC San Diego have demonstrated that one of biology's most essential enzymes can accurately read and transcribe an expanded genetic alphabet containing eight DNA letters instead of the four used by all known life. today.ucsd.edu

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